Deep learning enables fast, gentle STED microscopy

Deep learning enables fast, gentle STED microscopy

Blog Article

Abstract STED microscopy is widely used to image subcellular structures with super-resolution.Here, we report that restoring STED images with deep learning can mitigate photobleaching Fascinator and photodamage by reducing the pixel dwell time by one or two orders of magnitude.Our method allows for efficient and robust restoration of noisy 2D and 3D STED images 1964-1973 Engine - Valve Cover with multiple targets and facilitates long-term imaging of mitochondrial dynamics.